Improved method for synthesizing dolutegravir

The invention relates to an improved method for synthesizing dolutegravir and belongs to the field of medicinal chemistry. The method takes maltol (compound 1) as a raw material, and a target is synthesized by the following route. The process raw material is cheap and easy to obtain, a reaction solv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHANG FANGJIE, CHEN SHUIKU, ZHU SONGLIN, ZHU HUIFENG, CUI HAO, LI XUGUANG, LIU CONGJUN, LUO QI, MENG QINGLE, FANG SHUIXIA
Format: Patent
Sprache:chi ; eng
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