Method for synthesizing S-benzyl thioacetate on line through lipase catalysis
The invention discloses a method for synthesizing S-benzyl thioacetate on line through lipase catalysis. The method comprises the following steps: by taking dimethyl sulfoxide as a reaction solvent, taking methylbenzyl mercaptan and vinyl acetate as raw materials according to a mass ratio of 1: (0.5...
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| creator | LUO XIPING ZHOU NANI OU ZHIMIN SHEN LE DU LIHUA ZHANG WEN |
| description | The invention discloses a method for synthesizing S-benzyl thioacetate on line through lipase catalysis. The method comprises the following steps: by taking dimethyl sulfoxide as a reaction solvent, taking methylbenzyl mercaptan and vinyl acetate as raw materials according to a mass ratio of 1: (0.5 to 6), and taking lipase Lipozyme TL IM as a catalyst, placing the raw materials and the reaction solvent into an injector, uniformly filling a reaction channel of a microfluidic channel reactor with the lipase Lipozyme TL IM, and continuously feeding the raw materials and the reaction solvent intothe channel reactor for acylation reaction under pushing of an injection pump, wherein the inner diameter of the reaction channel of the microfluidic channel reactor is 0.8 to 2.4 mm, and the reaction channel is 0.5 to 1.0 m in length; controlling the acylation reaction temperature at 20 to 60 DEG C and the acylation reaction time for 20 to 40 min, collecting reaction liquid on line through a product collector, and treat |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE |
| title | Method for synthesizing S-benzyl thioacetate on line through lipase catalysis |
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