Novel technology of preparing thifluzamide from thiazole acid

The invention provides a novel technology of preparing thifluzamide from thiazole acid. The invention relates to a preparation method of a bactericide namely thifluzamide, and belongs to the technicalfield of chemistry. The invention discloses a one-step synthesis method of thifluzamide, and the synthesis method is simple and high efficient. According to the synthesis method, 2-methyl-4-trifluoromethyl-1,3-thiazole formic acid and 2,6-dibromo-trifluoromethoxyl aniline are taken as the primary raw materials, and the bactericide namely thifluzamide is synthesized in one step without any intermediate treatment in the presence of a catalyst. The novel technology has the advantages that the step is simple, there are few post treatment steps, and the reaction period is shortened. 种由噻唑酸制备噻呋酰胺的新型工艺。本发明涉及种杀菌剂噻呋酰胺的制备方法，属于化学技术领域。本发明公开了种简单高效步法制备噻呋酰胺的合成方法。以2-甲基-4-三氟甲基-1,3-噻唑甲酸、2,6-二溴-4-三氟甲氧基苯胺为起始原料，在催化剂存在的条件下，中间不处理步法合成杀菌剂噻呋酰胺。其优点是：步骤简单，反应后处理程序比较少，缩短了反应周期。