Preparing method of 2-amodogen-3-chlorobenznic methyl formate

The invention provides a preparing method of 2-amodogen-3-chlorobenzinc methyl formate. The preparing method comprises the steps of making 2-methyl anthranilate reacted with 1,3-dichlone-5,5-dimethylhydantoin (DDH), filtering out reacted reaction liquid, and afterwards conducting rectification to ob...

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Hauptverfasser: QIU JINGLEI, TIAN XIAOHONG, XIE SIMIAN, HUANG ZHIWEN, PAN FENGLIANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a preparing method of 2-amodogen-3-chlorobenzinc methyl formate. The preparing method comprises the steps of making 2-methyl anthranilate reacted with 1,3-dichlone-5,5-dimethylhydantoin (DDH), filtering out reacted reaction liquid, and afterwards conducting rectification to obtain 2-amodogen-chlorobenzinc methyl formate. By means of the preparing method of 2-amodogen-chlorobenzinc methyl formate, raw materials which are easy to obtain are utilized, the cost of the raw materials is lowered, the technological process is simplified, so that the product purity reaches as high as 99.5% or above, the total yield of the reaction and rectification reaches 40% or above, the product purity and the yield are high, and meanwhile, the preparing method is simpler and more feasible, and the industrialized production is better facilitated. 本发明提供种2-氨基-3-氯苯甲酸甲酯的制备方法,所述制备方法为:2-氨基苯甲酸甲酯与1,3-二氯-5,5-二甲基乙内酰脲(DDH)反应,将反应后的反应液过滤,而后精馏得到2-氨基-3-氯苯甲酸甲酯。本发明制备方法使用简单易得的原料,降低原料成本,简化工艺流程,使产物纯度高达99.5%以上,所述反应+精馏的总收率达到40%以上,