Garlic antimicrobial peptide AR117 and its application

The invention belongs to the field of biotechnology and specifically discloses a garlic antimicrobial peptide AR117 and its application. The applicant builds a garlic cDNA library and finally isolatesthe garlic antimicrobial peptide AR117. The garlic antimicrobial peptide AR117 has a sequence shown...

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Hauptverfasser: YANG MEI, DONG WUBEI, WU JIA, KONG XI
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the field of biotechnology and specifically discloses a garlic antimicrobial peptide AR117 and its application. The applicant builds a garlic cDNA library and finally isolatesthe garlic antimicrobial peptide AR117. The garlic antimicrobial peptide AR117 has a sequence shown in the formula of SEQ ID NO. 2. The applicant finds that the AR117 has a strong inhibitory effect on the growth of tomato canker, bacterial wilt, wheat seedlings and phytophthora capsici, which are difficult to be controlled by chemical drugs, can also inhibit bacillus cereus causing food poisoning, abdominal pain, vomiting and diarrhea and bacillus anthracis causing human anthracnose, and can effectively influence caenorhabditis elegans feeding. The hemolysis experiment result shows that the gene can inhibit nematodes and does not damage the mammals and human body. The antibacterial peptide gene is screened from garlic and can be used for biological control in the prevention and control ofplant diseases and insect