Pharmaceutical use of geniposidic acid in resisting enteritis
The invention relates to the field of medicine, and in particular, relates to a pharmaceutical use of geniposidic acid in resisting enteritis. The geniposidic acid has a new efficacy on resisting colitis. The compound has the advantages of remarkable curative effect and low toxic and side effects. A...
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| creator | ZOU YUANPING CAI JIAZHONG HUANG XIAOTAO ZHANG GUOHUI LIU MEIJING LIU CHANGHUI |
| description | The invention relates to the field of medicine, and in particular, relates to a pharmaceutical use of geniposidic acid in resisting enteritis. The geniposidic acid has a new efficacy on resisting colitis. The compound has the advantages of remarkable curative effect and low toxic and side effects. At present, NRF2 is showed to be a new target for treatment of colitis. Therefore, seeking of an NRF2traditional Chinese medicine agonist with high efficiency and low toxicity has traditional Chinese medicine significance. The geniposidic acid provided by the invention has the function of activatingthe NRF2 and plays a significant role in improving colitis by activating the intestinal NRF2. The geniposidic acid for treatment of colitis is a main effective ingredient of traditional Chinese medicine spreading hedyotis herb, is natural and has high safety.
本发明涉及医药学领域，特别是涉及种京尼平苷酸抗肠炎的医药用途。本发明的京尼平苷酸具有性抗大肠炎的新功效，该化合物具有疗效显著且毒副作用较低的优点：目前NRF2显示是治疗大肠炎的新靶点，因此，找寻高效、低毒的NRF2的中医药激动剂具有中药意义。本发明提供的京尼平苷酸具有激活NRF2的作用，通过激活肠NRF2，发挥显著的改善大肠炎的 |
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本发明涉及医药学领域，特别是涉及种京尼平苷酸抗肠炎的医药用途。本发明的京尼平苷酸具有性抗大肠炎的新功效，该化合物具有疗效显著且毒副作用较低的优点：目前NRF2显示是治疗大肠炎的新靶点，因此，找寻高效、低毒的NRF2的中医药激动剂具有中药意义。本发明提供的京尼平苷酸具有激活NRF2的作用，通过激活肠NRF2，发挥显著的改善大肠炎的</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180420&DB=EPODOC&CC=CN&NR=107929302A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180420&DB=EPODOC&CC=CN&NR=107929302A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZOU YUANPING</creatorcontrib><creatorcontrib>CAI JIAZHONG</creatorcontrib><creatorcontrib>HUANG XIAOTAO</creatorcontrib><creatorcontrib>ZHANG GUOHUI</creatorcontrib><creatorcontrib>LIU MEIJING</creatorcontrib><creatorcontrib>LIU CHANGHUI</creatorcontrib><title>Pharmaceutical use of geniposidic acid in resisting enteritis</title><description>The invention relates to the field of medicine, and in particular, relates to a pharmaceutical use of geniposidic acid in resisting enteritis. The geniposidic acid has a new efficacy on resisting colitis. The compound has the advantages of remarkable curative effect and low toxic and side effects. At present, NRF2 is showed to be a new target for treatment of colitis. Therefore, seeking of an NRF2traditional Chinese medicine agonist with high efficiency and low toxicity has traditional Chinese medicine significance. The geniposidic acid provided by the invention has the function of activatingthe NRF2 and plays a significant role in improving colitis by activating the intestinal NRF2. The geniposidic acid for treatment of colitis is a main effective ingredient of traditional Chinese medicine spreading hedyotis herb, is natural and has high safety.
本发明涉及医药学领域，特别是涉及种京尼平苷酸抗肠炎的医药用途。本发明的京尼平苷酸具有性抗大肠炎的新功效，该化合物具有疗效显著且毒副作用较低的优点：目前NRF2显示是治疗大肠炎的新靶点，因此，找寻高效、低毒的NRF2的中医药激动剂具有中药意义。本发明提供的京尼平苷酸具有激活NRF2的作用，通过激活肠NRF2，发挥显著的改善大肠炎的</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLANyEgsyk1MTi0tyUxOzFEoLU5VyE9TSE_NyyzIL85MyUxWSEzOTFHIzFMoSi3OLC7JzEtXSM0rSS3KLMks5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFQHPzUkvinf0MDcwtjSyNDYwcjYlRAwA69zBw</recordid><startdate>20180420</startdate><enddate>20180420</enddate><creator>ZOU YUANPING</creator><creator>CAI JIAZHONG</creator><creator>HUANG XIAOTAO</creator><creator>ZHANG GUOHUI</creator><creator>LIU MEIJING</creator><creator>LIU CHANGHUI</creator><scope>EVB</scope></search><sort><creationdate>20180420</creationdate><title>Pharmaceutical use of geniposidic acid in resisting enteritis</title><author>ZOU YUANPING ; CAI JIAZHONG ; HUANG XIAOTAO ; ZHANG GUOHUI ; LIU MEIJING ; LIU CHANGHUI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN107929302A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2018</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZOU YUANPING</creatorcontrib><creatorcontrib>CAI JIAZHONG</creatorcontrib><creatorcontrib>HUANG XIAOTAO</creatorcontrib><creatorcontrib>ZHANG GUOHUI</creatorcontrib><creatorcontrib>LIU MEIJING</creatorcontrib><creatorcontrib>LIU CHANGHUI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZOU YUANPING</au><au>CAI JIAZHONG</au><au>HUANG XIAOTAO</au><au>ZHANG GUOHUI</au><au>LIU MEIJING</au><au>LIU CHANGHUI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical use of geniposidic acid in resisting enteritis</title><date>2018-04-20</date><risdate>2018</risdate><abstract>The invention relates to the field of medicine, and in particular, relates to a pharmaceutical use of geniposidic acid in resisting enteritis. The geniposidic acid has a new efficacy on resisting colitis. The compound has the advantages of remarkable curative effect and low toxic and side effects. At present, NRF2 is showed to be a new target for treatment of colitis. Therefore, seeking of an NRF2traditional Chinese medicine agonist with high efficiency and low toxicity has traditional Chinese medicine significance. The geniposidic acid provided by the invention has the function of activatingthe NRF2 and plays a significant role in improving colitis by activating the intestinal NRF2. The geniposidic acid for treatment of colitis is a main effective ingredient of traditional Chinese medicine spreading hedyotis herb, is natural and has high safety.
本发明涉及医药学领域，特别是涉及种京尼平苷酸抗肠炎的医药用途。本发明的京尼平苷酸具有性抗大肠炎的新功效，该化合物具有疗效显著且毒副作用较低的优点：目前NRF2显示是治疗大肠炎的新靶点，因此，找寻高效、低毒的NRF2的中医药激动剂具有中药意义。本发明提供的京尼平苷酸具有激活NRF2的作用，通过激活肠NRF2，发挥显著的改善大肠炎的</abstract><oa>free_for_read</oa></addata></record> |
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| title | Pharmaceutical use of geniposidic acid in resisting enteritis |
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