Magnesium valproate sustained release tablet and preparation process thereof

The invention relates to a magnesium valproate sustained release tablet and a preparation process thereof. The magnesium valproate sustained release tablet is prepared from the following two parts: A,a tablet core prepared from the following substances: 29 to 54 percent of magnesium valproate, 17 to...

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Hauptverfasser: XIE XIANGMING, YANG ZHENHAO, YIN WENLE
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creator XIE XIANGMING
YANG ZHENHAO
YIN WENLE
description The invention relates to a magnesium valproate sustained release tablet and a preparation process thereof. The magnesium valproate sustained release tablet is prepared from the following two parts: A,a tablet core prepared from the following substances: 29 to 54 percent of magnesium valproate, 17 to 21 percent of hydroxypropyl methylcellulose, 2 to 9 percent of ethylcellulose, 22 to 30 percent ofethyl alcohol, 0.8 to 4 percent of magnesium stearate, and 3 to 7 percent of talcum powder; B, a sustained release tablet coating formula prepared from the following substances: 0.7 to 2 percent of ethylcellulose, 0.7 to 1.3 percent of glycerinum, 1.3 to 4 percent of hydroxypropyl methylcellulose, and 0.3 to 1.3 percent of talcum powder. The preparation process comprises: A, a preparation processof the tablet core, comprising the steps of weighing raw materials according to tablet core formula amounts uniformly mixing, adding an appropriate amount of the ethyl alcohol, preparing a soft material, sieving and pelletizin
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Magnesium valproate sustained release tablet and preparation process thereof
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