Preparation method for brivaracetam intermediate

The invention provides a preparation method for a brivaracetam intermediate. The method comprises the following steps that 1, a solvent, a fourth compound and a Pd/C catalyst are added into a reactionsystem; 2, the reaction system is placed at a hydrogen atmosphere and is subjected to an reaction for 2-3 hours; 3, the reaction is terminated, and filtration and decompression distillation are conducted to obtain the brivaracetam intermediate, namely the compound shown as the formula 3. According to the method, the reaction conditions are mild, the prepared brivaracetam intermediate compound islow in price and suitable for industrialized mass production, and the intermediate low in price is provided for preparation of brivaracetam. 本发明提供种制备布瓦西坦中间体的方法，所述方法包括以下步骤：(1)向反应体系加入溶剂、化合物4和Pd/C催化剂；(2)将反应体系置于氢气气氛下，反应2-3小时；(3)终止反应，过滤，减压蒸馏得到布瓦西坦中间体，即式3所示化合物。本发明方法反应条件温和，制备得到的布瓦西坦中间体化合物价格低，为布瓦西坦的制备提供了价格低廉的中间体，适于工业化大生产。