Norfloxacin composition

The invention relates to a norfloxacin composition and belongs to the technical field of pharmacy. According to the technical scheme provided by the invention, the norfloxacin composition is preparedfrom norfloxacin, lactose, cross-linked sodium carboxymethyl cellulose and other pharmaceutically acceptable auxiliary materials. The pharmaceutically acceptable auxiliary materials comprise a fillingagent and a lubricant and the granularity of the norfloxacin is distributed in a range that D90 is greater than or equal to 200mu m and less than or equal to 300mu m. The invention provides the stable norfloxacin composition with a dissolution behavior which is the same as that of an original research. 本发明涉及种诺氟沙星药物组合物，属于制药技术领域。本发明的技术方案是：种诺氟沙星组合物，包括诺氟沙星、乳糖、交联羧甲基纤维素钠及其他药学上可接受的辅料。所述药学上可接受的辅料包括填充剂和润滑剂，所述诺氟沙星粒度分布在200μm≤D90≤300μm范围。本发明提供了种溶出行为与原研致的稳定的诺氟沙星组合物。