Donepezil hydrochloride capsule and preparation method thereof
The invention belongs to the technical field of medicines, and particularly relates to a donepezil hydrochloride capsule and a preparation method thereof. The donepezil hydrochloride capsule is mainlyprepared from donepezil hydrochloride, octyl starch succinate, dextrin, polyethylene glycol 1000 vit...
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| creator | PAN XIN GAO WEI CONG HAIJIAN ZHU HUARONG ZHENG LU |
| description | The invention belongs to the technical field of medicines, and particularly relates to a donepezil hydrochloride capsule and a preparation method thereof. The donepezil hydrochloride capsule is mainlyprepared from donepezil hydrochloride, octyl starch succinate, dextrin, polyethylene glycol 1000 vitamin-E succinate, lactose, low-substituted hydroxypropyl cellulose, a hydroxypropyl methylcelluloseaqueous solution and magnesium stearate. The donepezil hydrochloride capsule has the advantages of high solubility and low content of relevant substances; and moreover, the gathering and condensationphenomenon of a content in the capsule can be avoided in the storage process, and the shelf life can be effectively prolonged. Meanwhile, the donepezil hydrochloride capsule also has the advantages of high bioavailability and high crystal stability, can achieve an effect of an imported donepezil hydrochloride tablet, can ensure a drug effect of the donepezil hydrochloride, and is an ideal donepezil hydrochloride capsule.
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Donepezil hydrochloride capsule and preparation method thereof |
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