Application of whole-blood 88-microRNA (Ribonucleic Acid) marker as diagnostic target of chronic liver disease

The invention discloses application of a whole-blood 88-microRNA (Ribonucleic Acid) marker as a diagnostic target of a chronic liver disease. Through a great number of studies, an inventor identifies one group of molecular tags consisting of 88 microRNAs; results show that the tag can be used for co...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZHENG XIAOFENG, ZHANG MEIYIN, WANG HUIYUN, LONG XIAORAN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention discloses application of a whole-blood 88-microRNA (Ribonucleic Acid) marker as a diagnostic target of a chronic liver disease. Through a great number of studies, an inventor identifies one group of molecular tags consisting of 88 microRNAs; results show that the tag can be used for completely distinguishing normal people, people with chronic hepatitis B, people with liver cirrhosis and people with liver cancer. For verifying a diagnostic function of the 88-microRNA tag, the inventor also collects another 63 whole-blood samples to form a verification group for verifying; the results show that the diagnosis accuracy rate of the 88-microRNA molecular tag is similar to that of an original normal diagnosis rate of a training group and further prove that the 88-microRNA molecular tag disclosed by the invention can be used for well distinguishing the normal people, the people with the chronic hepatitis B, the people with the liver cirrhosis and the people with the liver cancer. 本发明公开了全血88-microRNA标记物作