Adsorbent for eliminating low-density lipoprotein in blood and preparation method of adsorbent

The invention discloses an adsorbent for eliminating low-density lipoprotein in blood and a preparation method of the adsorbent. Hydrophobic aglucon and polyanion aglucon are coupled with an adsorption carrier, and the mass ratio of the hydrophobic aglucon to the polyanion aglucon ranges from (1:5)...

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Hauptverfasser: JIANG JIANMING, LIANG DAXING
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LIANG DAXING
description The invention discloses an adsorbent for eliminating low-density lipoprotein in blood and a preparation method of the adsorbent. Hydrophobic aglucon and polyanion aglucon are coupled with an adsorption carrier, and the mass ratio of the hydrophobic aglucon to the polyanion aglucon ranges from (1:5) to (5:1). By coupling the hydrophobic aglucon and the polyanion aglucon with the adsorption carrier simultaneously, and by virtue of high hydrophobic affinity of the hydrophobic aglucon with lipoprotein, and an electrostatic combination function of polyanion with the lipoprotein, specific adsorption is implemented through synergism of the hydrophobic aglucon and the polyanion with the lipoprotein, and thus the purpose of specifically eliminating TG (Triglyceride) and LDL (Low Density Lipoprotein) in blood is achieved. The adsorbent is a double-hydrophilic adsorbent which is high in adsorption capacity, good in biocompatibility and applicable to treatment on hyperlipidaemia through whole blood perfusion. 本发明公开了种用于清除
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Hydrophobic aglucon and polyanion aglucon are coupled with an adsorption carrier, and the mass ratio of the hydrophobic aglucon to the polyanion aglucon ranges from (1:5) to (5:1). By coupling the hydrophobic aglucon and the polyanion aglucon with the adsorption carrier simultaneously, and by virtue of high hydrophobic affinity of the hydrophobic aglucon with lipoprotein, and an electrostatic combination function of polyanion with the lipoprotein, specific adsorption is implemented through synergism of the hydrophobic aglucon and the polyanion with the lipoprotein, and thus the purpose of specifically eliminating TG (Triglyceride) and LDL (Low Density Lipoprotein) in blood is achieved. 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subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
title Adsorbent for eliminating low-density lipoprotein in blood and preparation method of adsorbent
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