Method for preparing Alpha-glucosidase inhibitor from Meretrix protein

The invention discloses a method for preparing Alpha-glucosidase inhibitor from Meretrix protein and belongs to the technical field of preparation of natural active substances. Meretrix protein is subjected as a raw material to drying and crushing, screened proteinase is added to carry out controlled enzymatic hydrolysis, and treatments such as enzyme deactivation and centrifuging are carried out to obtain enzymatic hydrolysate of Alpha-glucosidase inhibitor. Basis is laid for developing peptide Alpha-glucosidase inhibitors based on controlled enzymatic hydrolysis of the food material marine animal proteins, and exploring their wide application in foods and medicine. 本发明公开了种利用文蛤蛋白制备α-葡萄糖糖苷酶抑制剂的方法，属于天然活性物质制备技术领域。本发明方法以文蛤蛋白为原料，经过烘干、粉碎，加定量筛选出的蛋白酶进行可控酶解，经过灭酶、离心等处理，得到α-葡萄糖糖苷酶抑制剂的酶解液。本发明为开发基于食品原料海洋动物蛋白可控酶解后肽类的α-葡萄糖糖苷酶抑制剂以及探索其在食品、医学上的广泛应用奠定基础。