Xanthine oxidase inhibitor
The invention belongs to the technical field of medicine and relates to 2-(3-cyano/nitro-4-substituted phenyl)-4-methyl-2(i)H(/i)-1,2,3-triazole-4-methane acid and formyl hydrazine compounds shown in the formula I, medicinal salt and medicinal solvate and a preparation method thereof. The substituen...
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| creator | LI XIAONA WU YUE SHI AILONG WANG DEFA YAN SHUQI BAO KAI FENG DONGJIE ZHANG WEIGE GUAN QI WANG HE |
| description | The invention belongs to the technical field of medicine and relates to 2-(3-cyano/nitro-4-substituted phenyl)-4-methyl-2(i)H(/i)-1,2,3-triazole-4-methane acid and formyl hydrazine compounds shown in the formula I, medicinal salt and medicinal solvate and a preparation method thereof. The substituent definition of the compounds is defined as claim books and manuals. The invention further relates to application of the compounds in preparation of medicine for treatment of hyperuricemia and gout diseases.
本发明属于医药技术领域，涉及具有黄嘌呤氧化酶抑制活性的通式I的2-(3-氰基/硝基-4-取代苯基)-4-甲基-2-1,2,3-三氮唑-4-甲酸与甲酰肼类化合物、可药用的盐、可药用的溶剂化物及其制备方法，其中，化合物的各取代基定义如权利要求书和说明书所述。本发明还涉及这些化合物在制备治疗高尿酸血症及痛风病药物中的用途。（I）。 |
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本发明属于医药技术领域，涉及具有黄嘌呤氧化酶抑制活性的通式I的2-(3-氰基/硝基-4-取代苯基)-4-甲基-2-1,2,3-三氮唑-4-甲酸与甲酰肼类化合物、可药用的盐、可药用的溶剂化物及其制备方法，其中，化合物的各取代基定义如权利要求书和说明书所述。本发明还涉及这些化合物在制备治疗高尿酸血症及痛风病药物中的用途。（I）。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161123&DB=EPODOC&CC=CN&NR=106146419A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161123&DB=EPODOC&CC=CN&NR=106146419A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI XIAONA</creatorcontrib><creatorcontrib>WU YUE</creatorcontrib><creatorcontrib>SHI AILONG</creatorcontrib><creatorcontrib>WANG DEFA</creatorcontrib><creatorcontrib>YAN SHUQI</creatorcontrib><creatorcontrib>BAO KAI</creatorcontrib><creatorcontrib>FENG DONGJIE</creatorcontrib><creatorcontrib>ZHANG WEIGE</creatorcontrib><creatorcontrib>GUAN QI</creatorcontrib><creatorcontrib>WANG HE</creatorcontrib><title>Xanthine oxidase inhibitor</title><description>The invention belongs to the technical field of medicine and relates to 2-(3-cyano/nitro-4-substituted phenyl)-4-methyl-2(i)H(/i)-1,2,3-triazole-4-methane acid and formyl hydrazine compounds shown in the formula I, medicinal salt and medicinal solvate and a preparation method thereof. The substituent definition of the compounds is defined as claim books and manuals. The invention further relates to application of the compounds in preparation of medicine for treatment of hyperuricemia and gout diseases.
本发明属于医药技术领域，涉及具有黄嘌呤氧化酶抑制活性的通式I的2-(3-氰基/硝基-4-取代苯基)-4-甲基-2-1,2,3-三氮唑-4-甲酸与甲酰肼类化合物、可药用的盐、可药用的溶剂化物及其制备方法，其中，化合物的各取代基定义如权利要求书和说明书所述。本发明还涉及这些化合物在制备治疗高尿酸血症及痛风病药物中的用途。（I）。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJCKSMwrycjMS1XIr8hMSSxOVcjMy8hMyizJL-JhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoYGZoYmZiaGlo7GxKgBAF1eIzU</recordid><startdate>20161123</startdate><enddate>20161123</enddate><creator>LI XIAONA</creator><creator>WU YUE</creator><creator>SHI AILONG</creator><creator>WANG DEFA</creator><creator>YAN SHUQI</creator><creator>BAO KAI</creator><creator>FENG DONGJIE</creator><creator>ZHANG WEIGE</creator><creator>GUAN QI</creator><creator>WANG HE</creator><scope>EVB</scope></search><sort><creationdate>20161123</creationdate><title>Xanthine oxidase inhibitor</title><author>LI XIAONA ; WU YUE ; SHI AILONG ; WANG DEFA ; YAN SHUQI ; BAO KAI ; FENG DONGJIE ; ZHANG WEIGE ; GUAN QI ; WANG HE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN106146419A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LI XIAONA</creatorcontrib><creatorcontrib>WU YUE</creatorcontrib><creatorcontrib>SHI AILONG</creatorcontrib><creatorcontrib>WANG DEFA</creatorcontrib><creatorcontrib>YAN SHUQI</creatorcontrib><creatorcontrib>BAO KAI</creatorcontrib><creatorcontrib>FENG DONGJIE</creatorcontrib><creatorcontrib>ZHANG WEIGE</creatorcontrib><creatorcontrib>GUAN QI</creatorcontrib><creatorcontrib>WANG HE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI XIAONA</au><au>WU YUE</au><au>SHI AILONG</au><au>WANG DEFA</au><au>YAN SHUQI</au><au>BAO KAI</au><au>FENG DONGJIE</au><au>ZHANG WEIGE</au><au>GUAN QI</au><au>WANG HE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Xanthine oxidase inhibitor</title><date>2016-11-23</date><risdate>2016</risdate><abstract>The invention belongs to the technical field of medicine and relates to 2-(3-cyano/nitro-4-substituted phenyl)-4-methyl-2(i)H(/i)-1,2,3-triazole-4-methane acid and formyl hydrazine compounds shown in the formula I, medicinal salt and medicinal solvate and a preparation method thereof. The substituent definition of the compounds is defined as claim books and manuals. The invention further relates to application of the compounds in preparation of medicine for treatment of hyperuricemia and gout diseases.
本发明属于医药技术领域，涉及具有黄嘌呤氧化酶抑制活性的通式I的2-(3-氰基/硝基-4-取代苯基)-4-甲基-2-1,2,3-三氮唑-4-甲酸与甲酰肼类化合物、可药用的盐、可药用的溶剂化物及其制备方法，其中，化合物的各取代基定义如权利要求书和说明书所述。本发明还涉及这些化合物在制备治疗高尿酸血症及痛风病药物中的用途。（I）。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Xanthine oxidase inhibitor |
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