Application of polydatin in preparation of testis ischemia-reperfusion injury protective drugs

The invention relates to an application of polydatin in preparation of testis ischemia-reperfusion injury protective drugs. Reduction of testicular torsion refers to the process of ischemia-reperfusion injury which may affect male reproductive function and even cause dysgenesis, and there is still n...

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Bibliographische Detailangaben
Hauptverfasser: Qiao Huilian, Chen Hao, Li Zhen, Cao Wanjun
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to an application of polydatin in preparation of testis ischemia-reperfusion injury protective drugs. Reduction of testicular torsion refers to the process of ischemia-reperfusion injury which may affect male reproductive function and even cause dysgenesis, and there is still no effective way of clinical adjuvant therapy. At present, activity of anti-oxidative stress of polydatin in ischemia-reperfusion injury, especially in ischemia-reperfusion injury of tissues such as heart, brain and lung is researched widely, but there is no report about function and mechanism of polydatin in testis ischemia-reperfusion injury. According to the application of polydatin in preparation of testis ischemia-reperfusion injury protective drugs, testis injury can be treated, lipid peroxidation and enzymatic antioxidation defense systems during testis ischemia-reperfusion can be regulated, germ cell apoptosis caused by testis ischemia-reperfusion can be decreased, and apoptosis associated protein of testis