Organic compounds to treat hepatitis b virus

The disclosure relates to compositions comprising a HBV RNAi agent. In some embodiments, the HBV RNAi agent comprises a sense and an anti-sense strand, each strand being an 18-mer and the strands together forming a blunt-ended duplex, wherein the 3' end of at least one strand terminates in a ph...

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Hauptverfasser: GREENIDGE PAULETTE, HUESKEN DIETER, PATTERSON ANDREW, GOSSERT ALVAR, HOLDORF MEGHAN, BARYZA JEREMY LEE, WEILER JAN, FERNANDEZ CESAR, PATNAIK ANUP, RONDEAU JEAN-MICHEL RENE, ZHU MEICHENG, HUNZIKER JUERG, BLOMMERS MARCEL, GENO ERIN, NATT FRANCOIS JEANARLES
Format: Patent
Sprache:chi ; eng
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