Pharmaceutical composition containing fesoterodine and preparation method thereof
The invention brings forward a pharmaceutical composition containing fesoterodine and a preparation method thereof. The pharmaceutical composition also comprises a stabilizing agent, which is dextrin, maltodextrin, mannitol, propylene glycol and/or cane sugar. The preparation method of the pharmaceu...
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| creator | ZHA DAJUN GAO SONG CUI YUNLONG ZONG GUOJUN ZHANG XIAOLING |
| description | The invention brings forward a pharmaceutical composition containing fesoterodine and a preparation method thereof. The pharmaceutical composition also comprises a stabilizing agent, which is dextrin, maltodextrin, mannitol, propylene glycol and/or cane sugar. The preparation method of the pharmaceutical composition comprises steps of sieving, mixing, wetting, granulating, drying, tabletting and coating. According to the pharmaceutical composition, the problem that fesoterodine is easy to decompose under conditions of high temperature and high humidity is solved, and the problem that a medicinal excipient in an existing pharmaceutical composition containing fesoterodine has side effect on intestines and stomach is also solved.
本发明提出了种含非索罗定的药用组合物及其制备方法，所述药用组合物还包括稳定剂，所述稳定剂为糊精、麦芽糊精、甘露醇、丙二醇和/或蔗糖。所述药用组合物的制备方法包括过筛、混合、润湿、制粒、干燥、压片以及包衣步骤。该药用组合物不仅解决了非索罗定在高温和高湿条件下易分解的问题，还解决了现有非索罗定的药用组合物中药用赋形剂对肠胃副作用的问题。 |
| format | Patent |
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本发明提出了种含非索罗定的药用组合物及其制备方法，所述药用组合物还包括稳定剂，所述稳定剂为糊精、麦芽糊精、甘露醇、丙二醇和/或蔗糖。所述药用组合物的制备方法包括过筛、混合、润湿、制粒、干燥、压片以及包衣步骤。该药用组合物不仅解决了非索罗定在高温和高湿条件下易分解的问题，还解决了现有非索罗定的药用组合物中药用赋形剂对肠胃副作用的问题。</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160622&DB=EPODOC&CC=CN&NR=105687154A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160622&DB=EPODOC&CC=CN&NR=105687154A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHA DAJUN</creatorcontrib><creatorcontrib>GAO SONG</creatorcontrib><creatorcontrib>CUI YUNLONG</creatorcontrib><creatorcontrib>ZONG GUOJUN</creatorcontrib><creatorcontrib>ZHANG XIAOLING</creatorcontrib><title>Pharmaceutical composition containing fesoterodine and preparation method thereof</title><description>The invention brings forward a pharmaceutical composition containing fesoterodine and a preparation method thereof. The pharmaceutical composition also comprises a stabilizing agent, which is dextrin, maltodextrin, mannitol, propylene glycol and/or cane sugar. The preparation method of the pharmaceutical composition comprises steps of sieving, mixing, wetting, granulating, drying, tabletting and coating. According to the pharmaceutical composition, the problem that fesoterodine is easy to decompose under conditions of high temperature and high humidity is solved, and the problem that a medicinal excipient in an existing pharmaceutical composition containing fesoterodine has side effect on intestines and stomach is also solved.
本发明提出了种含非索罗定的药用组合物及其制备方法，所述药用组合物还包括稳定剂，所述稳定剂为糊精、麦芽糊精、甘露醇、丙二醇和/或蔗糖。所述药用组合物的制备方法包括过筛、混合、润湿、制粒、干燥、压片以及包衣步骤。该药用组合物不仅解决了非索罗定在高温和高湿条件下易分解的问题，还解决了现有非索罗定的药用组合物中药用赋形剂对肠胃副作用的问题。</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjUEKwjAQAHPxIOof4gMEi1a9SlE8iYL3siSbZqHZDcn6f4v4AE8zh4GZm-cjQkng8K3kYLROUpZKSsKTswIx8WADVlEs4onRAnubC2Yo8O0SahRvNWJBCUszCzBWXP24MOvr5dXdNpilx5qnF6P23b3ZtofTsWn3590_zQd94Djw</recordid><startdate>20160622</startdate><enddate>20160622</enddate><creator>ZHA DAJUN</creator><creator>GAO SONG</creator><creator>CUI YUNLONG</creator><creator>ZONG GUOJUN</creator><creator>ZHANG XIAOLING</creator><scope>EVB</scope></search><sort><creationdate>20160622</creationdate><title>Pharmaceutical composition containing fesoterodine and preparation method thereof</title><author>ZHA DAJUN ; GAO SONG ; CUI YUNLONG ; ZONG GUOJUN ; ZHANG XIAOLING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN105687154A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2016</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHA DAJUN</creatorcontrib><creatorcontrib>GAO SONG</creatorcontrib><creatorcontrib>CUI YUNLONG</creatorcontrib><creatorcontrib>ZONG GUOJUN</creatorcontrib><creatorcontrib>ZHANG XIAOLING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHA DAJUN</au><au>GAO SONG</au><au>CUI YUNLONG</au><au>ZONG GUOJUN</au><au>ZHANG XIAOLING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical composition containing fesoterodine and preparation method thereof</title><date>2016-06-22</date><risdate>2016</risdate><abstract>The invention brings forward a pharmaceutical composition containing fesoterodine and a preparation method thereof. The pharmaceutical composition also comprises a stabilizing agent, which is dextrin, maltodextrin, mannitol, propylene glycol and/or cane sugar. The preparation method of the pharmaceutical composition comprises steps of sieving, mixing, wetting, granulating, drying, tabletting and coating. According to the pharmaceutical composition, the problem that fesoterodine is easy to decompose under conditions of high temperature and high humidity is solved, and the problem that a medicinal excipient in an existing pharmaceutical composition containing fesoterodine has side effect on intestines and stomach is also solved.
本发明提出了种含非索罗定的药用组合物及其制备方法，所述药用组合物还包括稳定剂，所述稳定剂为糊精、麦芽糊精、甘露醇、丙二醇和/或蔗糖。所述药用组合物的制备方法包括过筛、混合、润湿、制粒、干燥、压片以及包衣步骤。该药用组合物不仅解决了非索罗定在高温和高湿条件下易分解的问题，还解决了现有非索罗定的药用组合物中药用赋形剂对肠胃副作用的问题。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Pharmaceutical composition containing fesoterodine and preparation method thereof |
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