Application of asymmetric aryl disulfide compounds serving as virus 3C protease inhibitors in preparation of antiviral drugs

The invention discloses an application of asymmetric aryl disulfide compounds serving as virus 3C protease inhibitors in preparation of antiviral drugs. The structural formula of the compounds is shown in the formula I or the formula II, wherein in the formula I, R1 represents mono-substituted groups or poly-substituted groups on a benzene ring and is independently selected from -NO2, C1-C3 alkyl, C1-C3 alkoxy, R'OCO- and a condensed ring constructed through direct condensation with the benzene ring, R' represents C1-C3 alkyl, R2 represents H or acyl with the number of carbon atoms being 1-3, and R3 represents H or C1-C3 alkyl; in the formula II, X represents NH or S, R4 represents mono-substituted groups or poly-substituted groups on the benzene ring, R1 is independently selected from -NO2, C1-C3 alkyl and halogen, R5 represents H or R''OCO-, R'' represents C1-C3 alkyl, R6 represents H or R''' CONH-, and R''' represents C1-C3 alkyl. The asymmetric aryl disulfide compounds can have an inhibition effect on CVB