Preparation method of anion exchange chromatography stationary phase

Preparation method of anion exchange chromatography stationary phase

The invention discloses a preparation method of an anion exchange chromatography stationary phase using highly-crosslinked glycidyl methacrylate-divinyl benzene microspheres as a matrix. The preparation method includes: adopting a dispersion polymerization method to prepare monodispersed linear poly...

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Hauptverfasser: ZHU YAN, LIU JUNWEI, ZHONG NAIFEI
Format: Patent
Sprache:chi ; eng
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CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
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creator ZHU YAN
LIU JUNWEI
ZHONG NAIFEI
description The invention discloses a preparation method of an anion exchange chromatography stationary phase using highly-crosslinked glycidyl methacrylate-divinyl benzene microspheres as a matrix. The preparation method includes: adopting a dispersion polymerization method to prepare monodispersed linear polystyrene seed microspheres; adopting a two-step seed swelling method to prepare highly-crosslinked glycidyl methacrylate-divinyl benzene copolymer microspheres; using methylamine, dimethylamine, trimethylamine, diethylamine, triethylamine and 1, 4-butane dioldiglycidyl ether as reaction raw materials to modify the highly-crosslinked glycidyl methacrylate-divinyl benzene copolymer microspheres to prepare the anion exchange chromatography stationary phase.
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subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
title Preparation method of anion exchange chromatography stationary phase
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