Indole oxoacetyl (N-diaryl methyl) piperazine derivatives and preparation method and application thereof

The invention relates to indole oxoacetyl (N-diaryl methyl) piperazine derivatives and a preparation method and application thereof, belongs to the technical field of pharmaceutical synthesis, and aims to provide new medicine with antitumor activity. The preparation method includes: in the presence of acid-binding agent, allowing indole oxoacetyl chloride to react with N-diaryl methyl piperazine so as to obtain the indole oxoacetyl (N-diaryl methyl) piperazine derivatives. The indole oxoacetyl (N-diaryl methyl) piperazine derivatives have the advantages that the indole oxoacetyl (N-diaryl methyl) piperazine derivatives have good tumor cell inhibiting activity, can be used as medicine and food for preventing or treating tumors, can be synthesized in one step, and are simple in process and easy to operate.