Cabozantinib intermediate 4-hydroxy-6,7-dimethoxyquinoline and preparation method thereof

The invention provides a cabozantinib intermediate 4-hydroxy-6,7-dimethoxyquinoline and a preparation method thereof. According to the method, ortho-formate, isopropylidene malonate and 3,4-dimethoxyaniline used as raw materials are subjected to condensation and cyclization reaction to obtain the 4-...

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Bibliographische Detailangaben
Hauptverfasser: CHEN ZENGFEI, FANG YING, CAI JIANPING, ZHANG LIFENG
Format: Patent
Sprache:eng
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