Tumor cell proliferation resistant medicinal composition and application thereof

The invention discloses a tumor cell proliferation resistant medicinal composition and an application thereof. The medicinal composition is prepared from an active component and an auxiliary material, wherein the active component is 3-bromo-N-((2S)-2-(4-fluorophenyl)-4-{3-[(9aS)-4-oxohexahydropyrazi...

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Bibliographische Detailangaben
Hauptverfasser: QIN JUNLI, TAN ZUOHUA, FU XUEXI, HOU LIYONG
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a tumor cell proliferation resistant medicinal composition and an application thereof. The medicinal composition is prepared from an active component and an auxiliary material, wherein the active component is 3-bromo-N-((2S)-2-(4-fluorophenyl)-4-{3-[(9aS)-4-oxohexahydropyrazino[2,1-c][1,4] oxazinyl-8(1H)-yl]azetidine-1-yl}butyl)-N-methyl-5-(trifluoromethyl)benzamide. Test shows that the above compound can inhibit growth of human breast cancer MCF-7 cells under a certain dosage within a certain period of time; and a light microscope observation result shows that the compound can induce tumor cells have cytoplasmic vacuoles and apoptotic body, so the compound has cancer cell proliferation inhibition bioactivity, and can be used to develop new antitumor medicines.