Synthesis method of tiamulin
The invention discloses a synthesis method of tiamulin. According to the method, firstly, p-toluene sulfonic acid pleuromutilin ester prepared by pleuromutilin is converted into sulpho-pleuromutilin. After that, sulpho-pleuromutilin reacts with the salt of an ethyl amino ethane derivative to generat...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The invention discloses a synthesis method of tiamulin. According to the method, firstly, p-toluene sulfonic acid pleuromutilin ester prepared by pleuromutilin is converted into sulpho-pleuromutilin. After that, sulpho-pleuromutilin reacts with the salt of an ethyl amino ethane derivative to generate tiamulin. The method is simple to operate, low in cost, and environment-friendly. The total recovery of tiamulin is over 80%. Therefore, the method is applied to the industrial production of tiamulin. |
|---|