Preparation method of natural scorpion venom polypeptide and application of natural scorpion venom polypeptide to bone marrow haematopoietic functional protection
The invention discloses a natural scorpion venom polypeptide. The natural scorpion venom polypeptide is a novel protein separated from scorpion venom of Buthus martensii Karsch and has a novel medicinal purpose on the aspect of bone marrow haematopoietic functional protection. A preparation method o...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LIU SIHONG KONG TIANHAN GUO QIFENG QIU YIFANG WANG CAIXIA JIANG LIYUAN DONG WEIHUA LI TING XING BAIQIAN WANG YAN |
| description | The invention discloses a natural scorpion venom polypeptide. The natural scorpion venom polypeptide is a novel protein separated from scorpion venom of Buthus martensii Karsch and has a novel medicinal purpose on the aspect of bone marrow haematopoietic functional protection. A preparation method of the natural scorpion venom polypeptide comprises the following steps of (1) collecting the scorpion venom of Buthus martensii Karsch; (2) separating SVPIV; (3) purifying BmKpp; (4) measuring the molecular weight and amino acid sequence of of BmKpp; and (5) measuring the bone marrow haematopoietic functional protection effect of BmKpp. BmKpp is a novel polypeptide from scorpion venom of Buthus martensii Karsch and has a remarkable bone marrow haematopoietic functional protection effect. BmKpp is single in component, precise in molecular weight, clear in total amino acid sequence, remarkable in cell proliferation promoting effect as well as standard and controllable in quality in the purification process so as to be beneficial to large-scale production. BmKpp has remarkable advantages and prospects on the aspects of bone marrow haematopoietic functional protection and development of drugs for preventing/protecting cell stress injury (radiotherapy, chemotherapy and the like). |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN104725498A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN104725498A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN104725498A3</originalsourceid><addsrcrecordid>eNqNjEsKwkAQRLNxIeod2gMIfiLqUoLiSly4D-2kQwZmppuZjuJ1PKlGPUBWRVH13jB7XSIJRlTLATxpwxVwDQG1jeggGY7STXcK7EHYPYVEbUWAoQIUcdb84H6UMtw4EHiMkR_QIHlUFrak1kDdBtPJPg6JrPQt42xQo0s0-ecomx4P1-I0I-GSkqChQFoW58U83yzX-W67X_X5vAFOGVhF</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Preparation method of natural scorpion venom polypeptide and application of natural scorpion venom polypeptide to bone marrow haematopoietic functional protection</title><source>esp@cenet</source><creator>LIU SIHONG ; KONG TIANHAN ; GUO QIFENG ; QIU YIFANG ; WANG CAIXIA ; JIANG LIYUAN ; DONG WEIHUA ; LI TING ; XING BAIQIAN ; WANG YAN</creator><creatorcontrib>LIU SIHONG ; KONG TIANHAN ; GUO QIFENG ; QIU YIFANG ; WANG CAIXIA ; JIANG LIYUAN ; DONG WEIHUA ; LI TING ; XING BAIQIAN ; WANG YAN</creatorcontrib><description>The invention discloses a natural scorpion venom polypeptide. The natural scorpion venom polypeptide is a novel protein separated from scorpion venom of Buthus martensii Karsch and has a novel medicinal purpose on the aspect of bone marrow haematopoietic functional protection. A preparation method of the natural scorpion venom polypeptide comprises the following steps of (1) collecting the scorpion venom of Buthus martensii Karsch; (2) separating SVPIV; (3) purifying BmKpp; (4) measuring the molecular weight and amino acid sequence of of BmKpp; and (5) measuring the bone marrow haematopoietic functional protection effect of BmKpp. BmKpp is a novel polypeptide from scorpion venom of Buthus martensii Karsch and has a remarkable bone marrow haematopoietic functional protection effect. BmKpp is single in component, precise in molecular weight, clear in total amino acid sequence, remarkable in cell proliferation promoting effect as well as standard and controllable in quality in the purification process so as to be beneficial to large-scale production. BmKpp has remarkable advantages and prospects on the aspects of bone marrow haematopoietic functional protection and development of drugs for preventing/protecting cell stress injury (radiotherapy, chemotherapy and the like).</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150624&DB=EPODOC&CC=CN&NR=104725498A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25565,76548</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150624&DB=EPODOC&CC=CN&NR=104725498A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIU SIHONG</creatorcontrib><creatorcontrib>KONG TIANHAN</creatorcontrib><creatorcontrib>GUO QIFENG</creatorcontrib><creatorcontrib>QIU YIFANG</creatorcontrib><creatorcontrib>WANG CAIXIA</creatorcontrib><creatorcontrib>JIANG LIYUAN</creatorcontrib><creatorcontrib>DONG WEIHUA</creatorcontrib><creatorcontrib>LI TING</creatorcontrib><creatorcontrib>XING BAIQIAN</creatorcontrib><creatorcontrib>WANG YAN</creatorcontrib><title>Preparation method of natural scorpion venom polypeptide and application of natural scorpion venom polypeptide to bone marrow haematopoietic functional protection</title><description>The invention discloses a natural scorpion venom polypeptide. The natural scorpion venom polypeptide is a novel protein separated from scorpion venom of Buthus martensii Karsch and has a novel medicinal purpose on the aspect of bone marrow haematopoietic functional protection. A preparation method of the natural scorpion venom polypeptide comprises the following steps of (1) collecting the scorpion venom of Buthus martensii Karsch; (2) separating SVPIV; (3) purifying BmKpp; (4) measuring the molecular weight and amino acid sequence of of BmKpp; and (5) measuring the bone marrow haematopoietic functional protection effect of BmKpp. BmKpp is a novel polypeptide from scorpion venom of Buthus martensii Karsch and has a remarkable bone marrow haematopoietic functional protection effect. BmKpp is single in component, precise in molecular weight, clear in total amino acid sequence, remarkable in cell proliferation promoting effect as well as standard and controllable in quality in the purification process so as to be beneficial to large-scale production. BmKpp has remarkable advantages and prospects on the aspects of bone marrow haematopoietic functional protection and development of drugs for preventing/protecting cell stress injury (radiotherapy, chemotherapy and the like).</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEsKwkAQRLNxIeod2gMIfiLqUoLiSly4D-2kQwZmppuZjuJ1PKlGPUBWRVH13jB7XSIJRlTLATxpwxVwDQG1jeggGY7STXcK7EHYPYVEbUWAoQIUcdb84H6UMtw4EHiMkR_QIHlUFrak1kDdBtPJPg6JrPQt42xQo0s0-ecomx4P1-I0I-GSkqChQFoW58U83yzX-W67X_X5vAFOGVhF</recordid><startdate>20150624</startdate><enddate>20150624</enddate><creator>LIU SIHONG</creator><creator>KONG TIANHAN</creator><creator>GUO QIFENG</creator><creator>QIU YIFANG</creator><creator>WANG CAIXIA</creator><creator>JIANG LIYUAN</creator><creator>DONG WEIHUA</creator><creator>LI TING</creator><creator>XING BAIQIAN</creator><creator>WANG YAN</creator><scope>EVB</scope></search><sort><creationdate>20150624</creationdate><title>Preparation method of natural scorpion venom polypeptide and application of natural scorpion venom polypeptide to bone marrow haematopoietic functional protection</title><author>LIU SIHONG ; KONG TIANHAN ; GUO QIFENG ; QIU YIFANG ; WANG CAIXIA ; JIANG LIYUAN ; DONG WEIHUA ; LI TING ; XING BAIQIAN ; WANG YAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN104725498A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LIU SIHONG</creatorcontrib><creatorcontrib>KONG TIANHAN</creatorcontrib><creatorcontrib>GUO QIFENG</creatorcontrib><creatorcontrib>QIU YIFANG</creatorcontrib><creatorcontrib>WANG CAIXIA</creatorcontrib><creatorcontrib>JIANG LIYUAN</creatorcontrib><creatorcontrib>DONG WEIHUA</creatorcontrib><creatorcontrib>LI TING</creatorcontrib><creatorcontrib>XING BAIQIAN</creatorcontrib><creatorcontrib>WANG YAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIU SIHONG</au><au>KONG TIANHAN</au><au>GUO QIFENG</au><au>QIU YIFANG</au><au>WANG CAIXIA</au><au>JIANG LIYUAN</au><au>DONG WEIHUA</au><au>LI TING</au><au>XING BAIQIAN</au><au>WANG YAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of natural scorpion venom polypeptide and application of natural scorpion venom polypeptide to bone marrow haematopoietic functional protection</title><date>2015-06-24</date><risdate>2015</risdate><abstract>The invention discloses a natural scorpion venom polypeptide. The natural scorpion venom polypeptide is a novel protein separated from scorpion venom of Buthus martensii Karsch and has a novel medicinal purpose on the aspect of bone marrow haematopoietic functional protection. A preparation method of the natural scorpion venom polypeptide comprises the following steps of (1) collecting the scorpion venom of Buthus martensii Karsch; (2) separating SVPIV; (3) purifying BmKpp; (4) measuring the molecular weight and amino acid sequence of of BmKpp; and (5) measuring the bone marrow haematopoietic functional protection effect of BmKpp. BmKpp is a novel polypeptide from scorpion venom of Buthus martensii Karsch and has a remarkable bone marrow haematopoietic functional protection effect. BmKpp is single in component, precise in molecular weight, clear in total amino acid sequence, remarkable in cell proliferation promoting effect as well as standard and controllable in quality in the purification process so as to be beneficial to large-scale production. BmKpp has remarkable advantages and prospects on the aspects of bone marrow haematopoietic functional protection and development of drugs for preventing/protecting cell stress injury (radiotherapy, chemotherapy and the like).</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_CN104725498A |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Preparation method of natural scorpion venom polypeptide and application of natural scorpion venom polypeptide to bone marrow haematopoietic functional protection |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T15%3A05%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LIU%20SIHONG&rft.date=2015-06-24&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN104725498A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |