Nerve conduit and preparation method thereof

The invention provides a nerve conduit. The nerve conduit is characterized by comprising an inner layer, an outer layer and a cavity; the outer surface of the inner layer is wrapped with the outer layer; the cavity is formed between the inner layer and the outer layer; the inner layer is a hydrophilic cytoskeleton layer manufactured by the electrostatic spinning method; the outer layer is a hydrophobic nerve conduit skeleton layer by the electrostatic spinning method; the cavity is used for storing a bioactive factor solution. The nerve conduit has the characteristics of being proper in strength and hardness, degradable, capable of providing proper neurotrophic active substances, ideal in double-layer or multi-layer structure, semi-permeable, low in cost, short in production cycle, easy to be stored and transported, free of viruses, free of immunological rejection or extremely small in immunological rejection, and wide in applicable scope; the requirement on nerve regeneration process can be met well.