Preparation method for apremilast and intermediate of apremilast

The invention relates to a preparation method for apremilast and an intermediate of the apremilast. The preparation method comprises the following steps: enabling 4-methoxy-3-ethoxybenzaldehyde to have Mannich reaction with methylsulfonylmethane and ammonia under the action of L-proline and a promot...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	SONG CHUNPENG, JU LIZHU, ZHOU LISHAN, CHEN JUN, LI XINFA, QI YUXIN
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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