Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof

Herein is reported a method for determining a combination of antigen binding sites comprising the steps of (i) determining the binding specificity and/or affinity and/or effector function and/or in vivo half-life of a multitude of bispecific antibodies prepared by combining each member of a first mu...

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Bibliographische Detailangaben
Hauptverfasser: NIEDERFELLNER GERHARD, HEINDL DIETER, TIEFENTHALER GEORG, HUELSMANN PETER MICHAEL, KOPETZKI ERHARD, KALUZA BRIGITTE
Format: Patent
Sprache:eng
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