Diterpenoid compounds having anti-tumor activity and application of diterpenoid compounds

The invention relates to diterpenoid compounds having anti-tumor activity and application of the diterpenoid compounds. Nine novel Briarane-type diterpenoid compounds Gemmacolides AS-BA having anti-tumor activity are separated from a marine animal dichotella gemmacea and in-vitro anti-tumor activity experiments confirm that the nine compounds have inhibiting effects on five cancer cells, namely, A549 (human lung cancer cells), HCT116 (human colon cancer cells), QGY-7703 (human liver cancer cells), U937 (human leukemia cells) and MG63 (human osteosarcoma cells) and thus the diterpenoid compounds can be used for preparation of anti-tumor drugs. The diterpenoid compounds provide leading compounds for development of novel anticancer drugs and are conducive to the development and application of marine medicinal resources.