Method for extracting and purifying calcium lactate
The invention discloses a method for extracting and purifying calcium lactate, and belongs to the technical field of biochemical engineering. The method comprises the following steps of removing impurities from a calcium lactate solution by centrifugation; adding a phase-separating solvent, mixing u...
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creator | WANG PING DAI GUIFU GAO HUIJIAO WU JIAN |
description | The invention discloses a method for extracting and purifying calcium lactate, and belongs to the technical field of biochemical engineering. The method comprises the following steps of removing impurities from a calcium lactate solution by centrifugation; adding a phase-separating solvent, mixing uniformly, standing for separating phases, taking an upper phase, crystallizing to obtain calcium lactate, wherein the phase-separating solvent is acetonitrile or a mixed solution formed by any one of acetonitrile, ethyl formate, methyl formate, methyl acetate, ethyl acetate, tetrahydrofuran and methyl ethyl ketone and any one of C1-C3 alcohol and C3-C5 alcohol. An extraction-crystallization method is adopted to extract and purify calcium lactate; calcium lactate can be crystallized naturally in the phase-separating solvent; a re-extraction step is omitted; and the process is simple and practicable. The phase-separating solvent has a low boiling point, can be recycled easily, has no toxicity or low toxicity, and is safe and environment-friendly. By adopting the method provided by the invention to extract and purify calcium lactate, a removal rate of impurities is high; a removal rate for pigment, protein and total sugar can reach 97%, 98% and 98% respectively; and the calcium lactate can be used for preparing high-purity lactic acid. The method is particularly suitable for calcium lactate fermentation broth prepared by straw hydrolysate with high impurity content. |
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The method comprises the following steps of removing impurities from a calcium lactate solution by centrifugation; adding a phase-separating solvent, mixing uniformly, standing for separating phases, taking an upper phase, crystallizing to obtain calcium lactate, wherein the phase-separating solvent is acetonitrile or a mixed solution formed by any one of acetonitrile, ethyl formate, methyl formate, methyl acetate, ethyl acetate, tetrahydrofuran and methyl ethyl ketone and any one of C1-C3 alcohol and C3-C5 alcohol. An extraction-crystallization method is adopted to extract and purify calcium lactate; calcium lactate can be crystallized naturally in the phase-separating solvent; a re-extraction step is omitted; and the process is simple and practicable. The phase-separating solvent has a low boiling point, can be recycled easily, has no toxicity or low toxicity, and is safe and environment-friendly. By adopting the method provided by the invention to extract and purify calcium lactate, a removal rate of impurities is high; a removal rate for pigment, protein and total sugar can reach 97%, 98% and 98% respectively; and the calcium lactate can be used for preparing high-purity lactic acid. The method is particularly suitable for calcium lactate fermentation broth prepared by straw hydrolysate with high impurity content.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150121&DB=EPODOC&CC=CN&NR=104292099A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150121&DB=EPODOC&CC=CN&NR=104292099A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG PING</creatorcontrib><creatorcontrib>DAI GUIFU</creatorcontrib><creatorcontrib>GAO HUIJIAO</creatorcontrib><creatorcontrib>WU JIAN</creatorcontrib><title>Method for extracting and purifying calcium lactate</title><description>The invention discloses a method for extracting and purifying calcium lactate, and belongs to the technical field of biochemical engineering. The method comprises the following steps of removing impurities from a calcium lactate solution by centrifugation; adding a phase-separating solvent, mixing uniformly, standing for separating phases, taking an upper phase, crystallizing to obtain calcium lactate, wherein the phase-separating solvent is acetonitrile or a mixed solution formed by any one of acetonitrile, ethyl formate, methyl formate, methyl acetate, ethyl acetate, tetrahydrofuran and methyl ethyl ketone and any one of C1-C3 alcohol and C3-C5 alcohol. An extraction-crystallization method is adopted to extract and purify calcium lactate; calcium lactate can be crystallized naturally in the phase-separating solvent; a re-extraction step is omitted; and the process is simple and practicable. The phase-separating solvent has a low boiling point, can be recycled easily, has no toxicity or low toxicity, and is safe and environment-friendly. By adopting the method provided by the invention to extract and purify calcium lactate, a removal rate of impurities is high; a removal rate for pigment, protein and total sugar can reach 97%, 98% and 98% respectively; and the calcium lactate can be used for preparing high-purity lactic acid. The method is particularly suitable for calcium lactate fermentation broth prepared by straw hydrolysate with high impurity content.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDD2TS3JyE9RSMsvUkitKClKTC7JzEtXSMxLUSgoLcpMqwTxkhNzkjNLcxVygLKJJak8DKxpiTnFqbxQmptB0c01xNlDN7UgPz61uCAxOTUvtSTe2c_QwMTI0sjA0tLRmBg1AAhWLI8</recordid><startdate>20150121</startdate><enddate>20150121</enddate><creator>WANG PING</creator><creator>DAI GUIFU</creator><creator>GAO HUIJIAO</creator><creator>WU JIAN</creator><scope>EVB</scope></search><sort><creationdate>20150121</creationdate><title>Method for extracting and purifying calcium lactate</title><author>WANG PING ; DAI GUIFU ; GAO HUIJIAO ; WU JIAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN104292099A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG PING</creatorcontrib><creatorcontrib>DAI GUIFU</creatorcontrib><creatorcontrib>GAO HUIJIAO</creatorcontrib><creatorcontrib>WU JIAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG PING</au><au>DAI GUIFU</au><au>GAO HUIJIAO</au><au>WU JIAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for extracting and purifying calcium lactate</title><date>2015-01-21</date><risdate>2015</risdate><abstract>The invention discloses a method for extracting and purifying calcium lactate, and belongs to the technical field of biochemical engineering. The method comprises the following steps of removing impurities from a calcium lactate solution by centrifugation; adding a phase-separating solvent, mixing uniformly, standing for separating phases, taking an upper phase, crystallizing to obtain calcium lactate, wherein the phase-separating solvent is acetonitrile or a mixed solution formed by any one of acetonitrile, ethyl formate, methyl formate, methyl acetate, ethyl acetate, tetrahydrofuran and methyl ethyl ketone and any one of C1-C3 alcohol and C3-C5 alcohol. An extraction-crystallization method is adopted to extract and purify calcium lactate; calcium lactate can be crystallized naturally in the phase-separating solvent; a re-extraction step is omitted; and the process is simple and practicable. The phase-separating solvent has a low boiling point, can be recycled easily, has no toxicity or low toxicity, and is safe and environment-friendly. By adopting the method provided by the invention to extract and purify calcium lactate, a removal rate of impurities is high; a removal rate for pigment, protein and total sugar can reach 97%, 98% and 98% respectively; and the calcium lactate can be used for preparing high-purity lactic acid. The method is particularly suitable for calcium lactate fermentation broth prepared by straw hydrolysate with high impurity content.</abstract><oa>free_for_read</oa></addata></record> |
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title | Method for extracting and purifying calcium lactate |
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