Experiment method for studying effect of tenuigenin on synaptic transmission of rat hippocampal neuron

Experiment method for studying effect of tenuigenin on synaptic transmission of rat hippocampal neuron

The invention discloses an experiment method for studying the effect of tenuigenin on synaptic transmission of rat hippocampal neuron. The method adopts a micro control instrument, a microscopic, and a recording electrode to monitor the spontaneous current state of neuron in tenuigenin with differen...

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Hauptverfasser: LIU WEIZHU, LI YUPING, CHEN CHONG, YAO LIHUA, LIU XINPING, SUN WEI, CHANG JUN, NAN XIAOHUA, MENG WEI, YUAN CHUNHUA
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Sprache:chi ; eng
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INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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creator LIU WEIZHU
LI YUPING
CHEN CHONG
YAO LIHUA
LIU XINPING
SUN WEI
CHANG JUN
NAN XIAOHUA
MENG WEI
YUAN CHUNHUA
description The invention discloses an experiment method for studying the effect of tenuigenin on synaptic transmission of rat hippocampal neuron. The method adopts a micro control instrument, a microscopic, and a recording electrode to monitor the spontaneous current state of neuron in tenuigenin with different concentrations, and then the monitor current data is analyzed so as to obtain the influence mechanism and effect of tenuigenin on rat hippocampal neuron. The method adopts a whole-cell patch-clamp technology to research the effect of tenuigenin on spontaneous postsynaptic current in the rat brain hippocampal CA1 area so as to disclose the regulating effect and mechanism of tenuigenin on neuron synaptic transmission, thus the requirements of scientific research and drug development are fulfilled, and at the same time a basis is provided for the further research on the signal transmission mechanism of neuron. The method can be widely used in the pharmaceutical theory researches on neuron, the experiment method and
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title Experiment method for studying effect of tenuigenin on synaptic transmission of rat hippocampal neuron
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