Polymerizable chitosan derivative and preparation method thereof

Polymerizable chitosan derivative and preparation method thereof

The invention discloses a polymerizable chitosan derivative and a preparation method thereof. According to the invention, benzaldehyde is used for protecting the amino group of 2-amino-4-pentenoic acid, and the material is subjected to a reaction with the amino group on chitosan; when the reaction i...

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1. Verfasser: GU YUXIA
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Sprache:chi ; eng
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CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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description The invention discloses a polymerizable chitosan derivative and a preparation method thereof. According to the invention, benzaldehyde is used for protecting the amino group of 2-amino-4-pentenoic acid, and the material is subjected to a reaction with the amino group on chitosan; when the reaction is finished, hydrochloric acid is used for deprotection, such that the polymerizable chitosan derivative is prepared. According to the invention, a double bond group which can be subjected to further polymerization reaction is introduced into chitosan molecular chain, such that the original biological activity and biocompatibility of chitosan are maintained in the obtained polymerizable chitosan derivative. During the preparation process, reaction conditions are mild, and the process is easy to control. According to the invention, a new chitosan derivative is provided, and chitosan modification range is expanded.
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
title Polymerizable chitosan derivative and preparation method thereof
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