Novel cephalosporin antibiotics and processes for preparation thereof

The present invention relates to a cephalosporin compound represented by the following general formula (I) : its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R represents hydrogen or an amino-protecting group, R and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: JONGAN LIM, CHAN-SIK BANG, JAE-HONG YEO
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to a cephalosporin compound represented by the following general formula (I) : its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R represents hydrogen or an amino-protecting group, R and R can be identical or different and independently of one another represent hydrogen or a hydroxy-protecting group, or R and R together can form a cyclic diol-protecting group, R represents hydrogen or a carboxyl-protecting group, R , R and R independently of one another represent hydrogen, amino or substituted amino, hydroxy, alkoxy, C1-4 alkyl, carboxyl or alkoxycarbonyl, or R and R together with the carbon atoms to which they are attached can form a C3-7 cycle, and Q represents CH or N, and to a process for preparation thereof and a pharmaceutical composition containing the compound (I) as an active ingredient.