Aminoalkyl-substituted n-thienyl benzamide derivative
The objective of the present invention is to provide a compound having inhibitory activity against an intestinal phosphate transporter (NPT-IIb), and useful as an active ingredient in a hyperphosphatemia therapeutic agent and/or preventive. A thiophene compound represented by formula (I) may be used...
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| creator | SATO IPPEI TERAI KAZUHIRO OKUDA TAKAO SI TIANYANG HACHIYA SHUNICHIRO WATANUKI SUSUMU ISOMURA MAI MIURA MASANORI KAGA DAISUKE |
| description | The objective of the present invention is to provide a compound having inhibitory activity against an intestinal phosphate transporter (NPT-IIb), and useful as an active ingredient in a hyperphosphatemia therapeutic agent and/or preventive. A thiophene compound represented by formula (I) may be used as a hyperphosphatemia therapeutic agent and/or preventive having NPT-IIb inhibitory activity. (In the formula, R1-6 each represent H or a lower alkyl or the like, L1-4 each represent a lower alkyl or the like, X1 represents CH2 or O, X2-3 each represent CH or N, k is 1-3, and n is 0-1.) |
| format | Patent |
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A thiophene compound represented by formula (I) may be used as a hyperphosphatemia therapeutic agent and/or preventive having NPT-IIb inhibitory activity. 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Aminoalkyl-substituted n-thienyl benzamide derivative |
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