Transdermal sustained-release drug delivery system and preparation and application method thereof

Transdermal sustained-release drug delivery system and preparation and application method thereof

The invention provides a formula of a transdermal sustained-release drug delivery system employing water-soluble polymer material as a substrate, a preparation method of the system, and an application of the preparation, wherein the substrate is formed by the mixing of polyvinyl alcohol, gelatin, so...

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Hauptverfasser: SHOU DAN, WANG XUPING, GUO QIAOYING, YU ZHONGMING, DONG YU, GAO JIAJIAN, ZHANG JIANMIN, WU RENJIE
Format: Patent
Sprache:chi ; eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator SHOU DAN
WANG XUPING
GUO QIAOYING
YU ZHONGMING
DONG YU
GAO JIAJIAN
ZHANG JIANMIN
WU RENJIE
description The invention provides a formula of a transdermal sustained-release drug delivery system employing water-soluble polymer material as a substrate, a preparation method of the system, and an application of the preparation, wherein the substrate is formed by the mixing of polyvinyl alcohol, gelatin, sodium carboxymethylcellulose, sorbitol, glycerin, sodium polyacrylate, castor oil and water. The substrate is large in drug loading capacity, good in affinity with various drugs including extracts of traditional Chinese medicines and chemical drugs, good in transdermal effect as the drug is sustainedly released in a transdermal manner, air-permeable, high in comfort level while being applied on skin, basically free of skin irritation and hypersensitivity reactions, and can be repeatedly used, thus being an ideal transdermal drug delivery platform. And various kinds of sustained-release transdermal delivery preparation can be prepared by combining with various drugs.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Transdermal sustained-release drug delivery system and preparation and application method thereof
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