Refinement method of crude potassium sodium dehydroandroan drographolide succinate product

The invention belongs to the field of medicine, particularly relates to a refinement method of a crude potassium sodium dehydroandroan drographolide succinate product and aims to provide a crude product refinement method for improving the synthesis yield of potassium sodium dehydroandroan drographol...

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Hauptverfasser: CUI YANGWEN, DENG XI, YANG CHENGFU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of medicine, particularly relates to a refinement method of a crude potassium sodium dehydroandroan drographolide succinate product and aims to provide a crude product refinement method for improving the synthesis yield of potassium sodium dehydroandroan drographolide succinate. According to the refinement method, a crude potassium sodium dehydroandroan drographolide succinate product is recrystallized to finally obtain a refined potassium sodium dehydroandroan drographolide succinate product. The refinement method comprises the following steps: A, decolorizing the crude potassium sodium dehydroandroan drographolide succinate product with active carbon in anhydrous ethanol; B, performing low-temperature crystallization; and C, filtering, washing with anhydrous ethanol, and drying to obtain the refined potassium sodium dehydroandroan drographolide succinate product. In the refinement process of the crude product, the anhydrous ethanol is used as refinement solvent; after dryi