Anti-alphavbeta6 antibodies

A monoclonal antibody or an antigen binding fragment thereof that (a) specifically binds to ±v²6 but does not bind other av integrins; and (b) does not inhibit the binding of ²6 to latency associated peptide (LAP) with an IC50 value lower than that of 10D5. Said monoclonal antibody, wherein the anti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LEONE DIANE R, SIMON KENNETH J, VIOLETTE SHEILA M, SHEPPARD DEAN, WEINREB PAUL H
Format: Patent
Sprache:chi ; eng
Schlagworte:
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