Trypsin-like serine protease inhibitors, and their preparation and use

The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SCHULZE ALEXANDER, DAGHISH MOHAMMED, REICHELT CLAUDIA, LUDWIG ALEXANDER, SCHWEINITZ ANDRE, HEROLD PETER, JELAKOVIC STJEPAN
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator SCHULZE ALEXANDER
DAGHISH MOHAMMED
REICHELT CLAUDIA
LUDWIG ALEXANDER
SCHWEINITZ ANDRE
HEROLD PETER
JELAKOVIC STJEPAN
description The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN102858744BB</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN102858744BB</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN102858744BB3</originalsourceid><addsrcrecordid>eNqNir0KwkAQBq-xEPUdDmsD_kRMnWCwskofVv0ki2Fv2T0L314RH8BqYGamoe3spc5SjPxAdBgLolrKIEdkGfjCOZmvIskt5gFsnwwlo8xJvvbpmIfJnUbH4sdZWLbHrjkV0NTDla4Q5L45b9bbal8dyrKud39Nb7cbNFI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Trypsin-like serine protease inhibitors, and their preparation and use</title><source>esp@cenet</source><creator>SCHULZE ALEXANDER ; DAGHISH MOHAMMED ; REICHELT CLAUDIA ; LUDWIG ALEXANDER ; SCHWEINITZ ANDRE ; HEROLD PETER ; JELAKOVIC STJEPAN</creator><creatorcontrib>SCHULZE ALEXANDER ; DAGHISH MOHAMMED ; REICHELT CLAUDIA ; LUDWIG ALEXANDER ; SCHWEINITZ ANDRE ; HEROLD PETER ; JELAKOVIC STJEPAN</creatorcontrib><description>The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150304&amp;DB=EPODOC&amp;CC=CN&amp;NR=102858744B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150304&amp;DB=EPODOC&amp;CC=CN&amp;NR=102858744B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SCHULZE ALEXANDER</creatorcontrib><creatorcontrib>DAGHISH MOHAMMED</creatorcontrib><creatorcontrib>REICHELT CLAUDIA</creatorcontrib><creatorcontrib>LUDWIG ALEXANDER</creatorcontrib><creatorcontrib>SCHWEINITZ ANDRE</creatorcontrib><creatorcontrib>HEROLD PETER</creatorcontrib><creatorcontrib>JELAKOVIC STJEPAN</creatorcontrib><title>Trypsin-like serine protease inhibitors, and their preparation and use</title><description>The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNir0KwkAQBq-xEPUdDmsD_kRMnWCwskofVv0ki2Fv2T0L314RH8BqYGamoe3spc5SjPxAdBgLolrKIEdkGfjCOZmvIskt5gFsnwwlo8xJvvbpmIfJnUbH4sdZWLbHrjkV0NTDla4Q5L45b9bbal8dyrKud39Nb7cbNFI</recordid><startdate>20150304</startdate><enddate>20150304</enddate><creator>SCHULZE ALEXANDER</creator><creator>DAGHISH MOHAMMED</creator><creator>REICHELT CLAUDIA</creator><creator>LUDWIG ALEXANDER</creator><creator>SCHWEINITZ ANDRE</creator><creator>HEROLD PETER</creator><creator>JELAKOVIC STJEPAN</creator><scope>EVB</scope></search><sort><creationdate>20150304</creationdate><title>Trypsin-like serine protease inhibitors, and their preparation and use</title><author>SCHULZE ALEXANDER ; DAGHISH MOHAMMED ; REICHELT CLAUDIA ; LUDWIG ALEXANDER ; SCHWEINITZ ANDRE ; HEROLD PETER ; JELAKOVIC STJEPAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN102858744BB3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SCHULZE ALEXANDER</creatorcontrib><creatorcontrib>DAGHISH MOHAMMED</creatorcontrib><creatorcontrib>REICHELT CLAUDIA</creatorcontrib><creatorcontrib>LUDWIG ALEXANDER</creatorcontrib><creatorcontrib>SCHWEINITZ ANDRE</creatorcontrib><creatorcontrib>HEROLD PETER</creatorcontrib><creatorcontrib>JELAKOVIC STJEPAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SCHULZE ALEXANDER</au><au>DAGHISH MOHAMMED</au><au>REICHELT CLAUDIA</au><au>LUDWIG ALEXANDER</au><au>SCHWEINITZ ANDRE</au><au>HEROLD PETER</au><au>JELAKOVIC STJEPAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Trypsin-like serine protease inhibitors, and their preparation and use</title><date>2015-03-04</date><risdate>2015</risdate><abstract>The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_CN102858744BB
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Trypsin-like serine protease inhibitors, and their preparation and use
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T10%3A45%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SCHULZE%20ALEXANDER&rft.date=2015-03-04&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN102858744BB%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true