Virus split deactivation method for human influenza virus split vaccine

The invention relates to a virus split deactivation method for a human influenza virus split vaccine, and belongs to the field of biological pharmacy. A method of firstly purifying and cracking H1N1 type, H3N2 type or B type monovalent influenza totivirus after gradient density centrifugal purificat...

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Hauptverfasser:	GU LIJUAN, KUANG KEWEI, HAN JUNHAI, GUO ZHANLONG, SONG ZEMIN, WU YEHONG, WANG CHUNPENG, WANG YAJUN, ZHAO DAPENG, BI YE, LIU XUGUANG, REN QI, XU WEN, FAN YUHONG, ZHANG XUEMEI, LI XIAOBO, GUO XUE, ZHAO ZHIFANG, SUN LIJUAN, LIU YIN, ZHANG CIQIANG, ZHANG YUHUI, GU JIANYANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a virus split deactivation method for a human influenza virus split vaccine, and belongs to the field of biological pharmacy. A method of firstly purifying and cracking H1N1 type, H3N2 type or B type monovalent influenza totivirus after gradient density centrifugal purification and then deactivating is adopted, so that the virus cracking effect can be improved, the deactivation time can be shortened, the deactivation efficiency can be increased, the using amount of a deactivator can be obviously reduced, deactivation operation steps can be simplified, the contamination risk can be reduced, factory buildings, facilities and energy consumption required for deactivation can be reduced, and the uniformity and the stability of deactivation can be increased.