Chitosan collagen membrane for guiding regeneration of peripheral bones of dental implant

The invention provides a chitosan collagen membrane for guiding regeneration of peripheral bones of a dental implant. The chitosan collagen membrane is prepared by performing mixing and freeze drying on a type I collagen aqueous solution and a chitosan acetic acid liquid in the volume ratio of 1:2,...

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Hauptverfasser: MIAO YUWEN, DONG YAN, WANG XINMU, LI JINGXIAO, MIAO ZHUOWEI, ZHANG DANDAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a chitosan collagen membrane for guiding regeneration of peripheral bones of a dental implant. The chitosan collagen membrane is prepared by performing mixing and freeze drying on a type I collagen aqueous solution and a chitosan acetic acid liquid in the volume ratio of 1:2, wherein the tensile strength is 0.532+/-0.1736 MPa, the average porosity is 90.95 percent, the membrane thickness is 0.30-0.50 millimeter, the average pore diameter is 15,642 nanometers, the elastic modules is 20.0+/-3.29 N/mm , the yield strength is 0.828+/-0.0763 MPa, and the elongation at break is 5.4+/-1.2 percent. In the chitosan collagen membrane, chitosan with rich source in nature and collagen with high biocompatibility are adopted; and as proved by an experiment, the chitosan collagen membrane does not influence the growth of osteoplast, is free from a remarkable inflammatory reaction on the back embedding region of a rabbit, has high biocompatibility, and is an absorbable membrane which has high biocompat