Inhibitors of the renal outer medullary potassium channel

This invention relates to compounds having structural Formula I: and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1). The compounds of Formula I are useful as diuretics and natriuretics and therefore are useful for the the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	PASTERNAK ALEXANDER, ZHU YUPING, TEUMELSAN NARDOS H, YANG LIHU, SHAHRIPOUR AURASH, TANG HAIFENG, WALSH SHAWN P
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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