Green synthesis method for ibuprofen piconol and medicinal preparation thereof
The invention discloses a green synthesis method for ibuprofen piconol and a medicinal preparation method thereof and provides a formula process of and a green chemical synthesis method of a medicinal compound, in particular the method for preparing ibuprofen piconol, a medicinal composition prepare...
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| creator | LONG TONG XIAO YANPING XIAO FANGQING WANG SHUHUA LIU XUTAO YANG SHIPING CHEN HAIBO |
| description | The invention discloses a green synthesis method for ibuprofen piconol and a medicinal preparation method thereof and provides a formula process of and a green chemical synthesis method of a medicinal compound, in particular the method for preparing ibuprofen piconol, a medicinal composition prepared by using ibuprofen piconol as an active ingredient, and a new formula of an externally-applied preparation for diminishing inflammation, relieving pain and treating infectious diseases. Compared with the prior art, the method has the advantages that: the technical route is advanced, the technical conditions are reasonable, the use of halogenating agents such as thionyl chloride which produce lots of toxic and harmful gases is avoided, a reactions are replaced by one reaction, the operation is simple, convenient and safe, the reaction yield is high, the reaction conditions are easy to control, the solvent and a dehydration condensation agent can be recycled and reused, the problems of trouble of treatment after a |
| format | Patent |
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Compared with the prior art, the method has the advantages that: the technical route is advanced, the technical conditions are reasonable, the use of halogenating agents such as thionyl chloride which produce lots of toxic and harmful gases is avoided, a reactions are replaced by one reaction, the operation is simple, convenient and safe, the reaction yield is high, the reaction conditions are easy to control, the solvent and a dehydration condensation agent can be recycled and reused, the problems of trouble of treatment after a</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120104&DB=EPODOC&CC=CN&NR=102304081A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120104&DB=EPODOC&CC=CN&NR=102304081A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LONG TONG</creatorcontrib><creatorcontrib>XIAO YANPING</creatorcontrib><creatorcontrib>XIAO FANGQING</creatorcontrib><creatorcontrib>WANG SHUHUA</creatorcontrib><creatorcontrib>LIU XUTAO</creatorcontrib><creatorcontrib>YANG SHIPING</creatorcontrib><creatorcontrib>CHEN HAIBO</creatorcontrib><title>Green synthesis method for ibuprofen piconol and medicinal preparation thereof</title><description>The invention discloses a green synthesis method for ibuprofen piconol and a medicinal preparation method thereof and provides a formula process of and a green chemical synthesis method of a medicinal compound, in particular the method for preparing ibuprofen piconol, a medicinal composition prepared by using ibuprofen piconol as an active ingredient, and a new formula of an externally-applied preparation for diminishing inflammation, relieving pain and treating infectious diseases. 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Green synthesis method for ibuprofen piconol and medicinal preparation thereof |
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