Agents targeting CD138 and uses thereof

Agents targeting CD138 and uses thereof

Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or ore homogenous binding to target cells.

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Bibliographische Detailangaben
Hauptverfasser: DAELKEN BENJAMIN, GERMER MATTHIAS, UHEREK CHRISTOPH, ZENG STEFFEN, AIGNER SILKE, BRUECHER CHRISTOPH, KRAUS ELMAR, OSTERROTH FRANK
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or ore homogenous binding to target cells.