Application of gentiamarin in preparing medicine for preventing and treating acute pancreatitis
The invention belongs to the field of traditional Chinese medicine preparation, relating to application of monomer gentiamarin extracted in the traditional Chinese medicine in preparing medicine for preventing and treating acute pancreatitis. In the invention, a model which is recognized by academic...
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| creator | SONG CHUNQING CHEN CHANGXUN LU JIAN JIN RUOMIN |
| description | The invention belongs to the field of traditional Chinese medicine preparation, relating to application of monomer gentiamarin extracted in the traditional Chinese medicine in preparing medicine for preventing and treating acute pancreatitis. In the invention, a model which is recognized by academic circles at home and abroad and is formed by continuously injecting caerulein to cause the acute pancreatitis of mice in enterocoelia and carrying out bezoar sodium taurocholate retrograde injection in cholangiopan so as to cause the acute pancreatitis of a rat, is adopted to study the action of the gentiamarin. The experiment result discloses that the gentiamarin has obvious function of resisting the acute pancreatitis caused by various reasons, and the action mechanism for resisting the acute pancreatitis is related to the releasing of the inflammatory factor, reduction of concentration of the tumor necrosis factor-alpha and interleukin-1beta in the serum or tissue, the increasing of the glutathione peroxidase ac |
| format | Patent |
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In the invention, a model which is recognized by academic circles at home and abroad and is formed by continuously injecting caerulein to cause the acute pancreatitis of mice in enterocoelia and carrying out bezoar sodium taurocholate retrograde injection in cholangiopan so as to cause the acute pancreatitis of a rat, is adopted to study the action of the gentiamarin. The experiment result discloses that the gentiamarin has obvious function of resisting the acute pancreatitis caused by various reasons, and the action mechanism for resisting the acute pancreatitis is related to the releasing of the inflammatory factor, reduction of concentration of the tumor necrosis factor-alpha and interleukin-1beta in the serum or tissue, the increasing of the glutathione peroxidase ac</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110112&DB=EPODOC&CC=CN&NR=101940582A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110112&DB=EPODOC&CC=CN&NR=101940582A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SONG CHUNQING</creatorcontrib><creatorcontrib>CHEN CHANGXUN</creatorcontrib><creatorcontrib>LU JIAN</creatorcontrib><creatorcontrib>JIN RUOMIN</creatorcontrib><title>Application of gentiamarin in preparing medicine for preventing and treating acute pancreatitis</title><description>The invention belongs to the field of traditional Chinese medicine preparation, relating to application of monomer gentiamarin extracted in the traditional Chinese medicine in preparing medicine for preventing and treating acute pancreatitis. 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The experiment result discloses that the gentiamarin has obvious function of resisting the acute pancreatitis caused by various reasons, and the action mechanism for resisting the acute pancreatitis is related to the releasing of the inflammatory factor, reduction of concentration of the tumor necrosis factor-alpha and interleukin-1beta in the serum or tissue, the increasing of the glutathione peroxidase ac</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNik0KwjAQhbNxIeodxgMIrT9Ql6Uorly5D0M6KQPtZEii57dRDyA8eO99fEtjW9WRHWYOAsHDQJIZJ4wsMEcjadkDTNSzYyHwIRb8KuLMUXrIkfB73DMTKIr7kMxpbRYex0SbX6_M9np5dLcdabCUFB0JZdvd66o-H6tTs28P_zhvygA9ig</recordid><startdate>20110112</startdate><enddate>20110112</enddate><creator>SONG CHUNQING</creator><creator>CHEN CHANGXUN</creator><creator>LU JIAN</creator><creator>JIN RUOMIN</creator><scope>EVB</scope></search><sort><creationdate>20110112</creationdate><title>Application of gentiamarin in preparing medicine for preventing and treating acute pancreatitis</title><author>SONG CHUNQING ; CHEN CHANGXUN ; LU JIAN ; JIN RUOMIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN101940582A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2011</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SONG CHUNQING</creatorcontrib><creatorcontrib>CHEN CHANGXUN</creatorcontrib><creatorcontrib>LU JIAN</creatorcontrib><creatorcontrib>JIN RUOMIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SONG CHUNQING</au><au>CHEN CHANGXUN</au><au>LU JIAN</au><au>JIN RUOMIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Application of gentiamarin in preparing medicine for preventing and treating acute pancreatitis</title><date>2011-01-12</date><risdate>2011</risdate><abstract>The invention belongs to the field of traditional Chinese medicine preparation, relating to application of monomer gentiamarin extracted in the traditional Chinese medicine in preparing medicine for preventing and treating acute pancreatitis. In the invention, a model which is recognized by academic circles at home and abroad and is formed by continuously injecting caerulein to cause the acute pancreatitis of mice in enterocoelia and carrying out bezoar sodium taurocholate retrograde injection in cholangiopan so as to cause the acute pancreatitis of a rat, is adopted to study the action of the gentiamarin. The experiment result discloses that the gentiamarin has obvious function of resisting the acute pancreatitis caused by various reasons, and the action mechanism for resisting the acute pancreatitis is related to the releasing of the inflammatory factor, reduction of concentration of the tumor necrosis factor-alpha and interleukin-1beta in the serum or tissue, the increasing of the glutathione peroxidase ac</abstract><oa>free_for_read</oa></addata></record> |
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| title | Application of gentiamarin in preparing medicine for preventing and treating acute pancreatitis |
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