Process for extracting and separating Angoroside C from radix scrophulariae and novel medical application of Angoroside C
The invention belongs to the pharmaceutical field of traditional Chinese medicine, relating to application of phenylpropanoid component-Angoroside C in traditional Chinese medicine of radix scrophulariae to preparing a medicament for preventing and treating myocardial hypertrophy, ventricular remode...
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| creator | SONG CHUNQING CHEN CHANGXUN MAO RENGANG JIN RUOMIN GU WEILIANG |
| description | The invention belongs to the pharmaceutical field of traditional Chinese medicine, relating to application of phenylpropanoid component-Angoroside C in traditional Chinese medicine of radix scrophulariae to preparing a medicament for preventing and treating myocardial hypertrophy, ventricular remodeling and congestive heart failure. The function of the Angoroside C is researched by utilizing a rat ventricle reconstruction model caused by abdominal aortic coarctation. Experimental results show that the Angoroside C improves symptoms of myocardial hypertrophy and ventricular remodeling and biological functions of myocardium through inhibiting related stimulating and mediated factors resulting in myocardial hypertrophy and ventricular remodeling. The Angoroside C has obvious inhibiting effects on cardiomyocyte hypertrophy and interstitial collagen remodeling, can balance myocardial collagen fiber metabolism, can be used for preparing the medicament for preventing and treating myocardial hypertrophy and ventricul |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | Process for extracting and separating Angoroside C from radix scrophulariae and novel medical application of Angoroside C |
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