Ceforanide C-type crystal composition for injection and preparation method thereof

The invention discloses a crystal preparation method for high-purity ceforanide hydrochloride A-type crystal, namely (6R,7R)-3-[[[1-(carboxymethyl-1H-tetrazole-5-group] sulfur] methyl butyl-7-[[[2-(aminomethyl)-phenyl]2 acyl] amino]8-oxo-5-thia-1-azabicyclo[4,2,0] octyl-2-vinyl-formic acid hydrochlo...

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Hauptverfasser:	YOU LI, LIU JIAJIAN, DENG SHENGQI, SHAO RUIJIE, LI BO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention discloses a crystal preparation method for high-purity ceforanide hydrochloride A-type crystal, namely (6R,7R)-3-[[[1-(carboxymethyl-1H-tetrazole-5-group] sulfur] methyl butyl-7-[[[2-(aminomethyl)-phenyl]2 acyl] amino]8-oxo-5-thia-1-azabicyclo[4,2,0] octyl-2-vinyl-formic acid hydrochloride and L-lysine B-type crystal respectively, crystal morphology parameters of the ceforanide hydrochloride A-type crystal and the L-lysine B-type crystal, and morphology parameters and medicinal application of ceforanide hydrochloride C-type crystal of sterile mixed powder consisting of the ceforanide hydrochloride A-type crystal and the L-lysine B-type crystal for injection for the first time.