Enantioselective reduction

The invention relates to a process for the preparation of a chiral compound, comprising enantioselectively reducing a carbon-carbon double bond of an alpha,beta-unsaturated compound in a mixture comprising both an E isomer and a Z isomer of the alpha,beta-unsaturated compound, wherein both E isomer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: STRAATMAN HENRICUS MARTINUS MARIA GERARDUS, VERZIJL GERARDUS KAREL MARIA, VERMOTE LINDA, VRIES DE ANDREAS HENDRIKUS MARIA, WILDEMAN DE STEFAAN MARIE ANDRE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a process for the preparation of a chiral compound, comprising enantioselectively reducing a carbon-carbon double bond of an alpha,beta-unsaturated compound in a mixture comprising both an E isomer and a Z isomer of the alpha,beta-unsaturated compound, wherein both E isomer and Z isomer are converted in the presence of a hydrogenation catalyst.