Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase
The present invention relates to a whole cell catalytic system for the preparation of an enantiomerically enriched alpha-amino acid from a corresponding hydantoin wherein hydantoinase, L-carbamoylase and hydantoin racemase are coexpressed in a recombinant micro-organism wherein the genes coding for...
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| creator | MAY OLIVER LANGE DE BEN SKRANC WOLFGANG HEEMSKERK DENNIS BOESTEN WILHELMUS HUBERTUS JOSEPH SARAKINOS GEORGIOS RUSNAK MUELLER MONIKA HERMSEN PETRUS JOHANNES |
| description | The present invention relates to a whole cell catalytic system for the preparation of an enantiomerically enriched alpha-amino acid from a corresponding hydantoin wherein hydantoinase, L-carbamoylase and hydantoin racemase are coexpressed in a recombinant micro-organism wherein the genes coding for these three enzymes are located on a single replicon. The present invention further relates to the use of such a whole cell catalytic system according in the preparation of an enantiomerically enriched L-alpha-amino acid from a corresponding hydantoin. |
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The present invention further relates to the use of such a whole cell catalytic system according in the preparation of an enantiomerically enriched L-alpha-amino acid from a corresponding hydantoin.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi70KAjEQhNNYiPoOa--BRwjWx6FYWR1YHuve6gU2PyRp8vam8AGsZr6Pma2anmsQ7ohFgLCg1GIJcs2FHVBwMdls_QcQ1rqgL8F6zHxqnJDYtQ7ol4aE6YUuVGlqrzZvlMyHX-7U8XadxnvHMcycY3t6LvP46M-9Mdpc9KD_2XwBjOs4ng</recordid><startdate>20091007</startdate><enddate>20091007</enddate><creator>MAY OLIVER</creator><creator>LANGE DE BEN</creator><creator>SKRANC WOLFGANG</creator><creator>HEEMSKERK DENNIS</creator><creator>BOESTEN WILHELMUS HUBERTUS JOSEPH</creator><creator>SARAKINOS GEORGIOS</creator><creator>RUSNAK MUELLER MONIKA</creator><creator>HERMSEN PETRUS JOHANNES</creator><scope>EVB</scope></search><sort><creationdate>20091007</creationdate><title>Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase</title><author>MAY OLIVER ; LANGE DE BEN ; SKRANC WOLFGANG ; HEEMSKERK DENNIS ; BOESTEN WILHELMUS HUBERTUS JOSEPH ; SARAKINOS GEORGIOS ; RUSNAK MUELLER MONIKA ; HERMSEN PETRUS JOHANNES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN101553573A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2009</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MAY OLIVER</creatorcontrib><creatorcontrib>LANGE DE BEN</creatorcontrib><creatorcontrib>SKRANC WOLFGANG</creatorcontrib><creatorcontrib>HEEMSKERK DENNIS</creatorcontrib><creatorcontrib>BOESTEN WILHELMUS HUBERTUS JOSEPH</creatorcontrib><creatorcontrib>SARAKINOS GEORGIOS</creatorcontrib><creatorcontrib>RUSNAK MUELLER MONIKA</creatorcontrib><creatorcontrib>HERMSEN PETRUS JOHANNES</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MAY OLIVER</au><au>LANGE DE BEN</au><au>SKRANC WOLFGANG</au><au>HEEMSKERK DENNIS</au><au>BOESTEN WILHELMUS HUBERTUS JOSEPH</au><au>SARAKINOS GEORGIOS</au><au>RUSNAK MUELLER MONIKA</au><au>HERMSEN PETRUS JOHANNES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase</title><date>2009-10-07</date><risdate>2009</risdate><abstract>The present invention relates to a whole cell catalytic system for the preparation of an enantiomerically enriched alpha-amino acid from a corresponding hydantoin wherein hydantoinase, L-carbamoylase and hydantoin racemase are coexpressed in a recombinant micro-organism wherein the genes coding for these three enzymes are located on a single replicon. The present invention further relates to the use of such a whole cell catalytic system according in the preparation of an enantiomerically enriched L-alpha-amino acid from a corresponding hydantoin.</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY SPIRITS VINEGAR WINE |
| title | Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase |
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