Therapeutic combinations comprising poly (adp-ribose) polymerases inhibitor

The invention generally relates to use of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one represented by Formula (1) as a chemosensitizer that enhances the efficacy of cytotoxic drugs or radiotherapy. This invention provides pharmaceutical combinations of...

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Hauptverfasser: HOSTOMSKY ZDENEK, JONES CHRISTOPHER, STEINFELDT HEIDI MARIE, CURTIN NICOLA JANE, CALVERT ALAN HILARY, BORITZKI THEODORE JAMES, THOMAS HUW DAVID, NEWELL DAVID RICHARD, DEWJI MOHAMED RAZA, KLAMERUS KAREN J, KAUFMAN RHONDA, STRATFORD IAN J, WILLIAMS KAY JANINE, PLUMMER ELIZABETH RUTH, REICH STEVEN D
Format: Patent
Sprache:chi ; eng
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