Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same
The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the foll...
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| creator | HOSHINO CHIKARA TOYOSHIMA TAKAHIRO TAKEDA MASAKAZU SASAKI TOSHINOBU |
| description | The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the following general formula (I): wherein Y 1 represents N or C(R 4 ) ; Y 2 represents N or C(R 5 ) ; R 4 and R 5 independently represent an alkyl group, a hydrogen atom etc. ; one of R 1 and R 2 represents an optionally substituted aryl group, an alkoxygroup or an optionally substituted heterocyclic group; the other of R 1 and R 2 represents a haloalkyl group, a cyanogroup, ahalogenatometc.; and R 3 represents a 5-tetrazolyl group or a carboxy group, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the same as an active ingredient. |
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That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the following general formula (I): wherein Y 1 represents N or C(R 4 ) ; Y 2 represents N or C(R 5 ) ; R 4 and R 5 independently represent an alkyl group, a hydrogen atom etc. ; one of R 1 and R 2 represents an optionally substituted aryl group, an alkoxygroup or an optionally substituted heterocyclic group; the other of R 1 and R 2 represents a haloalkyl group, a cyanogroup, ahalogenatometc.; and R 3 represents a 5-tetrazolyl group or a carboxy group, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the same as an active ingredient.</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20081008&DB=EPODOC&CC=CN&NR=101282936A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20081008&DB=EPODOC&CC=CN&NR=101282936A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HOSHINO CHIKARA</creatorcontrib><creatorcontrib>TOYOSHIMA TAKAHIRO</creatorcontrib><creatorcontrib>TAKEDA MASAKAZU</creatorcontrib><creatorcontrib>SASAKI TOSHINOBU</creatorcontrib><title>Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same</title><description>The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the following general formula (I): wherein Y 1 represents N or C(R 4 ) ; Y 2 represents N or C(R 5 ) ; R 4 and R 5 independently represent an alkyl group, a hydrogen atom etc. ; one of R 1 and R 2 represents an optionally substituted aryl group, an alkoxygroup or an optionally substituted heterocyclic group; the other of R 1 and R 2 represents a haloalkyl group, a cyanogroup, ahalogenatometc.; and R 3 represents a 5-tetrazolyl group or a carboxy group, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the same as an active ingredient.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAj1yywpyk9PzUssSU1RyEgtSS3KT65MzslMVkjOzy3IL81LUUgE4oKMxKLcxOTU0pLM5MQciFxxZklmfh6YXZRZnJmXrlCSkapQnJibysPAmpaYU5zKC6W5GRTdXEOcPXRTC_LjU4sLgAblpZbEO_sZGhgaWRhZGps5GhOjBgB4IjpP</recordid><startdate>20081008</startdate><enddate>20081008</enddate><creator>HOSHINO CHIKARA</creator><creator>TOYOSHIMA TAKAHIRO</creator><creator>TAKEDA MASAKAZU</creator><creator>SASAKI TOSHINOBU</creator><scope>EVB</scope></search><sort><creationdate>20081008</creationdate><title>Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same</title><author>HOSHINO CHIKARA ; TOYOSHIMA TAKAHIRO ; TAKEDA MASAKAZU ; SASAKI TOSHINOBU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN101282936A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2008</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>HOSHINO CHIKARA</creatorcontrib><creatorcontrib>TOYOSHIMA TAKAHIRO</creatorcontrib><creatorcontrib>TAKEDA MASAKAZU</creatorcontrib><creatorcontrib>SASAKI TOSHINOBU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HOSHINO CHIKARA</au><au>TOYOSHIMA TAKAHIRO</au><au>TAKEDA MASAKAZU</au><au>SASAKI TOSHINOBU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same</title><date>2008-10-08</date><risdate>2008</risdate><abstract>The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the following general formula (I): wherein Y 1 represents N or C(R 4 ) ; Y 2 represents N or C(R 5 ) ; R 4 and R 5 independently represent an alkyl group, a hydrogen atom etc. ; one of R 1 and R 2 represents an optionally substituted aryl group, an alkoxygroup or an optionally substituted heterocyclic group; the other of R 1 and R 2 represents a haloalkyl group, a cyanogroup, ahalogenatometc.; and R 3 represents a 5-tetrazolyl group or a carboxy group, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the same as an active ingredient.</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same |
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