Mutant porcine reproductive and respiratory syndrome virus

The present invention provides a genetically modified PRRS virus which has been modified such that the conserved cysteine in the E protein has been deleted or changed to a non-cysteine residue and polynucleotides that encode it. Vaccines comprising the genetically modified virus and polynucleotides...

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1. Verfasser: YOO DONG WAN,LEE CHANG HEE,CALVERT JAY GREGORY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a genetically modified PRRS virus which has been modified such that the conserved cysteine in the E protein has been deleted or changed to a non-cysteine residue and polynucleotides that encode it. Vaccines comprising the genetically modified virus and polynucleotides are also provided.